Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer
Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer
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Author / Creator
Tanaka, Toshihiro , Atsumi, Naho , Nakamura, Naohiro , Yanai, Hirotsugu , Komai, Yoshihiro , Omachi, Taichi , Tanaka, Kiyomichi , Ishigaki, Kazuhiko , Saiga, Kazuho , Ohsugi, Haruyuki , Tokuyama, Yoko , Imahashi, Yuki , Hisha, Hiroko , Yoshida, Naoko , Kumano, Keiki , Okazaki, Kazuichi and Ueno, Hiroo
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
We recently reported that the polycomb complex protein Bmi1 is a marker for lingual epithelial stem cells (LESCs), which are involved in the long-term maintenance of lingual epithelial tissue in the physiological state. However, the precise role of LESCs in generating tongue tumors and Bmi1-positive cell lineage dynamics in tongue cancers are uncle...
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Full title
Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5177893
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5177893
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep39386
