Modulation of GLO1 Expression Affects Malignant Properties of Cells
Modulation of GLO1 Expression Affects Malignant Properties of Cells
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The energy metabolism of most tumor cells relies on aerobic glycolysis (Warburg effect) characterized by an increased glycolytic flux that is accompanied by the increased formation of the cytotoxic metabolite methylglyoxal (MGO). Consequently, the rate of detoxification of this reactive glycolytic byproduct needs to be increased in order to prevent...
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Full title
Modulation of GLO1 Expression Affects Malignant Properties of Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187933
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms17122133