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Modulation of GLO1 Expression Affects Malignant Properties of Cells

Modulation of GLO1 Expression Affects Malignant Properties of Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187933

Modulation of GLO1 Expression Affects Malignant Properties of Cells

About this item

Full title

Modulation of GLO1 Expression Affects Malignant Properties of Cells

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2016-12, Vol.17 (12), p.2133-2133

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The energy metabolism of most tumor cells relies on aerobic glycolysis (Warburg effect) characterized by an increased glycolytic flux that is accompanied by the increased formation of the cytotoxic metabolite methylglyoxal (MGO). Consequently, the rate of detoxification of this reactive glycolytic byproduct needs to be increased in order to prevent...

Alternative Titles

Full title

Modulation of GLO1 Expression Affects Malignant Properties of Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187933

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187933

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms17122133

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