Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Dia...
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
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Author / Creator
Corella, Dolores , Coltell, Oscar , Sorlí, Jose V , Estruch, Ramón , Quiles, Laura , Martínez-González, Miguel Ángel , Salas-Salvadó, Jordi , Castañer, Olga , Arós, Fernando , Ortega-Calvo, Manuel , Serra-Majem, Lluís , Gómez-Gracia, Enrique , Portolés, Olga , Fiol, Miquel , Díez Espino, Javier , Basora, Josep , Fitó, Montserrat , Ros, Emilio and Ordovás, José M
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Nutrigenetic studies analyzing gene-diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover, TCF7L2-rs7903146 is one of the most influential variants in T2D-genetic risk scores (GRS). Therefore, to incr...
Alternative Titles
Full title
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
Authors, Artists and Contributors
Author / Creator
Coltell, Oscar
Sorlí, Jose V
Estruch, Ramón
Quiles, Laura
Martínez-González, Miguel Ángel
Salas-Salvadó, Jordi
Castañer, Olga
Arós, Fernando
Ortega-Calvo, Manuel
Serra-Majem, Lluís
Gómez-Gracia, Enrique
Portolés, Olga
Fiol, Miquel
Díez Espino, Javier
Basora, Josep
Fitó, Montserrat
Ros, Emilio
Ordovás, José M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5188448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5188448
Other Identifiers
ISSN
2072-6643
E-ISSN
2072-6643
DOI
10.3390/nu8120793