Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in...
Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells
About this item
Full title
Author / Creator
Hirashita, Yuka , Tsukamoto, Yoshiyuki , Yanagihara, Kazuyoshi , Fumoto, Shoichi , Hijiya, Naoki , Nakada, Chisato , Uchida, Tomohisa , Matsuura, Keiko , Kodama, Masaaki , Okimoto, Tadayoshi , Daa, Tsutomu , Seike, Masataka , Iha, Hidekatsu , Shirao, Kuniaki , Murakami, Kazunari and Moriyama, Masatsugu
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Gastric cancer (GC) is characterized by amplifications of receptor tyrosine kinases (RTK) and KRAS, therefore, targeting of the RTK/KRAS downstream pathways could help to broaden the applicability of molecular targeted therapy for GC. We assembled a panel of 48 GC cell lines and screened predictors of responsiveness to inhibition of the RAF/MEK/ERK...
Alternative Titles
Full title
Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5198963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5198963
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.13094
