NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
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Publisher
United States: Nature Publishing Group
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Language
English
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Publisher
United States: Nature Publishing Group
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Contents
Altered metabolism has been implicated in the pathogenesis of inflammatory diseases. NADPH oxidase 4 (NOX4), a source of cellular superoxide anions, has multiple biological functions that may be of importance in inflammation and in the pathogenesis of human metabolic diseases, including diabetes. However, the mechanisms by which NOX4-dependent meta...
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Full title
NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5204248
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5204248
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4153
