Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Key Points
Loss-of-function (LOF) technologies are widely used across many model organisms and many fields.
Although all LOF approaches have the shared goal of perturbing gene function, there are complex differences between approaches that can have a considerable effect on the outcome of experiments.
The specific properties and effect of e...
Alternative Titles
Full title
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5206767
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5206767
Other Identifiers
ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/nrg.2016.118