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The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3...

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5214942

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

About this item

Full title

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2017-01, Vol.14 (1), p.127-142

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammasomes are important for maintaining intestinal homeostasis, and dysbiosis contributes to the pathology of inflammatory bowel disease (IBD) and increases the risk for colorectal cancer, Inflammasome defects contribute to chronic intestinal inflammation and increase the susceptibility to colitis in mice, However, the inflammasome sensor absen...

Alternative Titles

Full title

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5214942

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5214942

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/cmi.2016.35

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