Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations
Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations
About this item
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Author / Creator
Huang, Zhiyong , Hong, Quan , Zhang, Xueguang , Xiao, Wenzhen , Wang, Liyuan , Cui, Shaoyuan , Feng, Zhe , Lv, Yang , Cai, Guangyan , Chen, Xiangmei and Wu, Di
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Uric acid (UA) is an antioxidant found in human serum. However, high UA levels may also have pro-oxidant functions. According to previous research, aldose reductase (AR) plays a vital role in the oxidative stress-related complications of diabetes. We sought to determine the mechanism by which UA becomes deleterious at high concentrations as well as...
Alternative Titles
Full title
Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5217275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5217275
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-016-0158-6
