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Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model...

Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5220363

Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes

About this item

Full title

Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-01, Vol.7 (1), p.39604-39604, Article 39604

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Serelaxin prevents endothelial dysfunction in the mouse aorta
ex vivo
and inhibits apoptosis in cardiomyocytes under acute hyperglycaemia. Less is known about the effects of serelaxin in an
in vivo
mouse model of diabetes. Therefore, we tested the hypothesis in streptozotocin (STZ)-treated mice that serelaxin is able to reverse diabetes...

Alternative Titles

Full title

Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5220363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5220363

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep39604

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