Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
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Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Centrosomes are the principal microtubule organising centres in somatic cells. Abnormal centrosome number is common in tumours and occurs after γ‐irradiation and in cells with mutations in DNA repair genes. To investigate how DNA damage causes centrosome amplification, we examined cells that conditionally lack the Rad51 recombinase and thereby incu...
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Full title
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_522792
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_522792
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7600393
