Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercap...
Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
About this item
Full title
Author / Creator
Hanaoka, Kenjiro , Sasakura, Kiyoshi , Suwanai, Yusuke , Toma-Fukai, Sachiko , Shimamoto, Kazuhito , Takano, Yoko , Shibuya, Norihiro , Terai, Takuya , Komatsu, Toru , Ueno, Tasuku , Ogasawara, Yuki , Tsuchiya, Yukihiro , Watanabe, Yasuo , Kimura, Hideo , Wang, Chao , Uchiyama, Masanobu , Kojima, Hirotatsu , Okabe, Takayoshi , Urano, Yasuteru , Shimizu, Toshiyuki and Nagano, Tetsuo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Very recent studies indicate that sulfur atoms with oxidation state 0 or −1, called sulfane sulfurs, are the actual mediators of some physiological processes previously considered to be regulated by hydrogen sulfide (H
2
S). 3-Mercaptopyruvate sulfurtransferase (3MST), one of three H
2
S-producing enzymes, was also recently shown to pro...
Alternative Titles
Full title
Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Authors, Artists and Contributors
Author / Creator
Sasakura, Kiyoshi
Suwanai, Yusuke
Toma-Fukai, Sachiko
Shimamoto, Kazuhito
Takano, Yoko
Shibuya, Norihiro
Terai, Takuya
Komatsu, Toru
Ueno, Tasuku
Ogasawara, Yuki
Tsuchiya, Yukihiro
Watanabe, Yasuo
Kimura, Hideo
Wang, Chao
Uchiyama, Masanobu
Kojima, Hirotatsu
Okabe, Takayoshi
Urano, Yasuteru
Shimizu, Toshiyuki
Nagano, Tetsuo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228037
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228037
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep40227
