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Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228369

Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

About this item

Full title

Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

Publisher

Greece: D.A. Spandidos

Journal title

Oncology letters, 2016-12, Vol.12 (6), p.4850-4856

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

A total of two major isoforms, cyclin D1a and cyclin D1b, are generated from the human cyclin D1 gene by alternative splicing. Cyclin D1b is scarcely expressed in normal tissues; however, it is expressed at a high frequency in certain types of cancerous tissue. The present authors previously constructed cyclin D1b transgenic (Tg) mice and identifie...

Alternative Titles

Full title

Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228369

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228369

Other Identifiers

ISSN

1792-1074

E-ISSN

1792-1082

DOI

10.3892/ol.2016.5286

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