The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
About this item
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Author / Creator
Sacramento, Carolina Q. , de Melo, Gabrielle R. , de Freitas, Caroline S. , Rocha, Natasha , Hoelz, Lucas Villas Bôas , Miranda, Milene , Fintelman-Rodrigues, Natalia , Marttorelli, Andressa , Ferreira, André C. , Barbosa-Lima, Giselle , Abrantes, Juliana L. , Vieira, Yasmine Rangel , Bastos, Mônica M. , de Mello Volotão, Eduardo , Nunes, Estevão Portela , Tschoeke, Diogo A. , Leomil, Luciana , Loiola, Erick Correia , Trindade, Pablo , Rehen, Stevens K. , Bozza, Fernando A. , Bozza, Patrícia T. , Boechat, Nubia , Thompson, Fabiano L. , de Filippis, Ana M. B. , Brüning, Karin and Souza, Thiago Moreno L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Zika virus (ZIKV) is a member of the
Flaviviridae
family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes neurological disorders during fetal development and in adulthood, antiviral drugs are necessary. Sofosbuvir is clinically approved for use against HCV and targets the...
Alternative Titles
Full title
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
Authors, Artists and Contributors
Author / Creator
de Melo, Gabrielle R.
de Freitas, Caroline S.
Rocha, Natasha
Hoelz, Lucas Villas Bôas
Miranda, Milene
Fintelman-Rodrigues, Natalia
Marttorelli, Andressa
Ferreira, André C.
Barbosa-Lima, Giselle
Abrantes, Juliana L.
Vieira, Yasmine Rangel
Bastos, Mônica M.
de Mello Volotão, Eduardo
Nunes, Estevão Portela
Tschoeke, Diogo A.
Leomil, Luciana
Loiola, Erick Correia
Trindade, Pablo
Rehen, Stevens K.
Bozza, Fernando A.
Bozza, Patrícia T.
Boechat, Nubia
Thompson, Fabiano L.
de Filippis, Ana M. B.
Brüning, Karin
Souza, Thiago Moreno L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5241873
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5241873
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep40920