CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency
CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The mechanisms of how signaling pathways are coordinated and integrated for the maintenance of the self-renewal of human embryonic stem cells (hESCs) and the acquisition of pluripotency in reprogramming are still only partly understood. CDK1 is a key regulator of mitosis. Recently, CDK1 has been shown to be involved in regulating self-renewal of st...
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CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5260505
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5260505
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2016.84
