Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
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Author / Creator
Jia, Rongjie , Liang, Yingchao , Chen, Rui , Liu, Guoke , Wang, Hao , Tang, Min , Zhou, Xuyu , Wang, Huajing , Yang, Yang , Wei, Huafeng , Li, Bohua , Song, Yipeng and Zhao, Jian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tumor metastasis leads to high mortality; therefore, understanding the mechanisms that underlie tumor metastasis is crucial. Generally seen as a secretory protein, osteopontin (OPN) is involved in multifarious pathophysiological events. Here, we present a novel pro-metastatic role of OPN during metastatic colonization. Unlike secretory OPN (sOPN),...
Alternative Titles
Full title
Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5261026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5261026
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2016.422
