Log in to save to my catalogue

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the...

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5264595

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

About this item

Full title

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-01, Vol.7 (1), p.41309, Article 41309

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene
CCNE2
seems to play an important role in resistance to trastuzumab therapy. Cell viability was evaluated in trastuzumab treated HER2+ BT474 wt (sensi...

Alternative Titles

Full title

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5264595

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5264595

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep41309

How to access this item