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RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-...

RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5269742

RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis

About this item

Full title

RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-01, Vol.7 (1), p.41517-41517, Article 41517

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The nonsense mediated decay (NMD) pathway is a critical surveillance mechanism for identifying aberrant mRNA transcripts. It is unknown, however, whether the NMD system is affected by seizures
in vivo
and whether changes confer beneficial or maladaptive responses that influence long-term outcomes such the network alterations that produce spon...

Alternative Titles

Full title

RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5269742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5269742

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep41517

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