RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-...
RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The nonsense mediated decay (NMD) pathway is a critical surveillance mechanism for identifying aberrant mRNA transcripts. It is unknown, however, whether the NMD system is affected by seizures
in vivo
and whether changes confer beneficial or maladaptive responses that influence long-term outcomes such the network alterations that produce spon...
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RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5269742
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5269742
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep41517