A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: th...
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
About this item
Full title
Author / Creator
Tharkeshwar, Arun Kumar , Trekker, Jesse , Vermeire, Wendy , Pauwels, Jarne , Sannerud, Ragna , Priestman, David A. , te Vruchte, Danielle , Vints, Katlijn , Baatsen, Pieter , Decuypere, Jean-Paul , Lu, Huiqi , Martin, Shaun , Vangheluwe, Peter , Swinnen, Johannes V. , Lagae, Liesbet , Impens, Francis , Platt, Frances M. , Gevaert, Kris and Annaert, Wim
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Superparamagnetic iron oxide nanoparticles (SPIONs) have mainly been used as cellular carriers for genes and therapeutic products, while their use in subcellular organelle isolation remains underexploited. We engineered SPIONs targeting distinct subcellular compartments. Dimercaptosuccinic acid-coated SPIONs are internalized and accumulate in late...
Alternative Titles
Full title
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
Authors, Artists and Contributors
Author / Creator
Trekker, Jesse
Vermeire, Wendy
Pauwels, Jarne
Sannerud, Ragna
Priestman, David A.
te Vruchte, Danielle
Vints, Katlijn
Baatsen, Pieter
Decuypere, Jean-Paul
Lu, Huiqi
Martin, Shaun
Vangheluwe, Peter
Swinnen, Johannes V.
Lagae, Liesbet
Impens, Francis
Platt, Frances M.
Gevaert, Kris
Annaert, Wim
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278418
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278418
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep41408
