Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lym...
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas
About this item
Full title
Author / Creator
Abate, Francesco , da Silva-Almeida, Ana C. , Zairis, Sakellarios , Robles-Valero, Javier , Couronne, Lucile , Khiabanian, Hossein , Quinn, S. Aidan , Kim, Mi-Yeon , Laginestra, Maria Antonella , Kim, Christine , Fiore, Danilo , Bhagat, Govind , Piris, Miguel Angel , Campo, Elias , Lossos, Izidore S. , Bernard, Olivier A. , Inghirami, Giorgio , Pileri, Stefano , Bustelo, Xosé R. , Rabadan, Raul , Ferrando, Adolfo A. and Palomero, Teresa
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of non-Hodgkin lymphomas frequently associated with poor prognosis and for which genetic mechanisms of transformation remain incompletely understood. Using RNA sequencing and targeted sequencing, here we identify a recurrent in-frame deletion (VAV1 Δ778–786) generated by a focal deletion...
Alternative Titles
Full title
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas
Authors, Artists and Contributors
Author / Creator
da Silva-Almeida, Ana C.
Zairis, Sakellarios
Robles-Valero, Javier
Couronne, Lucile
Khiabanian, Hossein
Quinn, S. Aidan
Kim, Mi-Yeon
Laginestra, Maria Antonella
Kim, Christine
Fiore, Danilo
Bhagat, Govind
Piris, Miguel Angel
Campo, Elias
Lossos, Izidore S.
Bernard, Olivier A.
Inghirami, Giorgio
Pileri, Stefano
Bustelo, Xosé R.
Rabadan, Raul
Ferrando, Adolfo A.
Palomero, Teresa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278460
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278460
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1608839114