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Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278468

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

About this item

Full title

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (4), p.E610-E618

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The signaling mechanisms that choreograph the assembly of the highly asymmetric pre- and postsynaptic structures are still poorly defined. Using synaptosome fractionation, immunostaining, and coimmunoprecipitation, we found that Celsr3 and Vangl2, core components of the planar cell polarity (PCP) pathway, are localized at developing glutamatergic s...

Alternative Titles

Full title

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278468

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278468

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1612062114

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