Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation
Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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The signaling mechanisms that choreograph the assembly of the highly asymmetric pre- and postsynaptic structures are still poorly defined. Using synaptosome fractionation, immunostaining, and coimmunoprecipitation, we found that Celsr3 and Vangl2, core components of the planar cell polarity (PCP) pathway, are localized at developing glutamatergic s...
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Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278468
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5278468
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1612062114