Mitochondrial mutations and metabolic adaptation in pancreatic cancer
Mitochondrial mutations and metabolic adaptation in pancreatic cancer
About this item
Full title
Author / Creator
Australian Pancreatic Cancer Genome Initiative , Hardie, Rae-Anne , van Dam, Ellen , Cowley, Mark , Han, Ting-Li , Balaban, Seher , Pajic, Marina , Pinese, Mark , Iconomou, Mary , Shearer, Robert F , McKenna, Jessie , Miller, David , Waddell, Nicola , Pearson, John V , Grimmond, Sean M , Sazanov, Leonid , Biankin, Andrew V , Villas-Boas, Silas , Hoy, Andrew J , Turner, Nigel and Saunders, Darren N
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Pancreatic cancer has a five-year survival rate of ~8%, with characteristic molecular heterogeneity and restricted treatment options. Targeting metabolism has emerged as a potentially effective therapeutic strategy for cancers such as pancreatic cancer, which are driven by genetic alterations that are not tractable drug targets. Although somatic mi...
Alternative Titles
Full title
Mitochondrial mutations and metabolic adaptation in pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Hardie, Rae-Anne
van Dam, Ellen
Cowley, Mark
Han, Ting-Li
Balaban, Seher
Pajic, Marina
Pinese, Mark
Iconomou, Mary
Shearer, Robert F
McKenna, Jessie
Miller, David
Waddell, Nicola
Pearson, John V
Grimmond, Sean M
Sazanov, Leonid
Biankin, Andrew V
Villas-Boas, Silas
Hoy, Andrew J
Turner, Nigel
Saunders, Darren N
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5282905
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5282905
Other Identifiers
ISSN
2049-3002
E-ISSN
2049-3002
DOI
10.1186/s40170-017-0164-1
