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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5284333

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

We have recently shown that non-viral gene therapy can stabilise the decline of lung function in patients with cystic fibrosis (CF). However, the effect was modest, and more potent gene transfer agents are still required. Fuson protein (F)/Hemagglutinin/Neuraminidase protein (HN)-pseudotyped lentiviral vectors are more efficient for lung gene trans...

Alternative Titles

Full title

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5284333

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5284333

Other Identifiers

ISSN

0040-6376

E-ISSN

1468-3296

DOI

10.1136/thoraxjnl-2016-208406

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