COX2/mPGES1/PGE₂ pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-deri...
COX2/mPGES1/PGE₂ pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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In recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)–mediated inhibition of activated PD-1⁺ T lymphocytes plays a major role in tumor escape from immune system during cancer progression. Lately, the anti–PD-L1 and –PD-1 immune therapies have become an important tool for treatment of advanced human cancers, in...
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COX2/mPGES1/PGE₂ pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293015
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293015
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1612920114
