Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contrac...
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Mitochondrial fusion is thought to be important for supporting cardiac contractility, but is hardly detectable in cultured cardiomyocytes and is difficult to directly evaluate in the heart. We overcame this obstacle through in vivo adenoviral transduction with matrix-targeted photoactivatable GFP and confocal microscopy. Imaging in whole rat hearts...
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Full title
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293028
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293028
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1617288114