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Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contrac...

Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contrac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293028

Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity

About this item

Full title

Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.E859-E868

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mitochondrial fusion is thought to be important for supporting cardiac contractility, but is hardly detectable in cultured cardiomyocytes and is difficult to directly evaluate in the heart. We overcame this obstacle through in vivo adenoviral transduction with matrix-targeted photoactivatable GFP and confocal microscopy. Imaging in whole rat hearts...

Alternative Titles

Full title

Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293028

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5293028

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1617288114

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