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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5294412

Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

About this item

Full title

Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-02, Vol.7 (1), p.41977, Article 41977

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Defective autophagy and deranged metabolic pathways are common in cancer; pharmacologic targeting of these two pathways could provide a viable therapeutic option. However, how these pathways are regulated by limited availability of growth factors is still unknown. Our study shows that HSulf-1 (endosulfatase), a known tumor suppressor which attenuat...

Alternative Titles

Full title

Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5294412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5294412

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep41977

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