Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer
Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Defective autophagy and deranged metabolic pathways are common in cancer; pharmacologic targeting of these two pathways could provide a viable therapeutic option. However, how these pathways are regulated by limited availability of growth factors is still unknown. Our study shows that HSulf-1 (endosulfatase), a known tumor suppressor which attenuat...
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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5294412
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5294412
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep41977