Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage
Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The highly reactive dicarbonyl methylglyoxal (MGO) is mainly formed as byproduct of glycolysis. Therefore, high blood glucose levels determine increased MGO accumulation. Nonetheless, MGO levels are also increased as consequence of the ineffective action of its main detoxification pathway, the glyoxalase system, of which glyoxalase 1 (Glo1) is the...
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Full title
Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5297820
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5297820
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms18010188
