First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and gr...
First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation
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Author / Creator
NISC Comparative Sequencing Program , Dewan, Ramita , Pemov, Alexander , Dutra, Amalia S. , Pak, Evgenia D. , Edwards, Nancy A. , Ray-Chaudhury, Abhik , Hansen, Nancy F. , Chandrasekharappa, Settara C. , Mullikin, James C. , Asthagiri, Ashok R. , Heiss, John D. , Stewart, Douglas R. and Germanwala, Anand V.
Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
Neurofibromatosis type 2 (NF2) is a rare autosomal dominant nervous system tumor predisposition disorder caused by constitutive inactivation of one of the two copies of NF2. Meningiomas affect about one half of NF2 patients, and are associated with a higher disease burden. Currently, the somatic mutation landscape in NF2-associated meningiomas rema...
Alternative Titles
Full title
First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5307647
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5307647
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-017-3127-6
