Gsk3 is a metabolic checkpoint regulator in B cells
Gsk3 is a metabolic checkpoint regulator in B cells
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Full title
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Mature B cells remain in a quiescent state until activated. Rickert and colleagues identify a prominent role for the kinase Gsk3 in resting naive B cells and in activated germinal center B cells that restrains the production of Myc and reactive oxygen species and prevents metabolic collapse.
B cells predominate in a quiescent state until an anti...
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Full title
Gsk3 is a metabolic checkpoint regulator in B cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310963
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3664
