Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Editorial Summary
Discovery and characterization of two Brønsted acid enzymes from quinolone alkaloid biosynthesis provides new biocatalytic approaches for the challenging but synthetically useful cationic rearrangement of epoxides.
Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during tot...
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Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310975
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310975
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2283