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Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis

Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310975

Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis

About this item

Full title

Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2017-03, Vol.13 (3), p.325-332

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Editorial Summary
Discovery and characterization of two Brønsted acid enzymes from quinolone alkaloid biosynthesis provides new biocatalytic approaches for the challenging but synthetically useful cationic rearrangement of epoxides.
Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during tot...

Alternative Titles

Full title

Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310975

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5310975

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.2283

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