Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for ca...
Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy
About this item
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Author / Creator
Aliperta, Roberta , Welzel, Petra B. , Bergmann, Ralf , Freudenberg, Uwe , Berndt, Nicole , Feldmann, Anja , Arndt, Claudia , Koristka, Stefanie , Stanzione, Marcello , Cartellieri, Marc , Ehninger, Armin , Ehninger, Gerhard , Werner, Carsten , Pietzsch, Jens , Steinbach, Jörg , Bornhäuser, Martin and Bachmann, Michael P.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
Combining stem cells with biomaterial scaffolds provides a promising strategy for the development of drug delivery systems. Here we propose an innovative immunotherapeutic organoid by housing human mesenchymal stromal cells (MSCs), gene-modified for the secretion of an anti-CD33-anti-CD3 bispecific antibody (bsAb), in a small biocompatible star-sha...
Alternative Titles
Full title
Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5311951
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5311951
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep42855
