Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynog...
Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)
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Author / Creator
Cui, Zhongkai , Liu, Yun , Wang, Wenwen , Wang, Qian , Zhang, Ning , Lin, Fan , Wang, Na , Shao, Changwei , Dong, Zhongdian , Li, Yangzhen , Yang, Yingming , Hu, Mengzhu , Li, Hailong , Gao, Fengtao , Wei, Zhanfei , Meng, Liang , Liu, Yang , Wei, Min , Zhu, Ying , Guo, Hua , Cheng, Christopher H. K. , Schartl, Manfred and Chen, Songlin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chinese tongue sole is a marine fish with ZW sex determination. Genome sequencing suggested that the Z-linked
dmrt1
is a putative male determination gene, but direct genetic evidence is still lacking. Here we show that TALEN of
dmrt1
efficiently induced mutations of this gene. The ZZ
dmrt1
mutant fish developed ovary-like testis,...
Alternative Titles
Full title
Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5311979
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5311979
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep42213
