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Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells

Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5314375

Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells

About this item

Full title

Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-02, Vol.7 (1), p.42409-42409, Article 42409

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

CK2 is a ubiquitous, constitutively active, highly pleiotropic, acidophilic Ser/Thr protein kinase whose holoenzyme is composed of two catalytic (α and/or α’) subunits and a dimer of a non-catalytic β subunit. Abnormally high CK2 level/activity is often associated with malignancy and a variety of cancer cells have been shown to rely on it to escape...

Alternative Titles

Full title

Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5314375

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5314375

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep42409

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