Correcting mitochondrial fusion by manipulating mitofusin conformations
Correcting mitochondrial fusion by manipulating mitofusin conformations
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
Mitochondria are dynamic organelles that exchange contents and undergo remodelling during cyclic fusion and fission. Genetic mutations in
MFN2
(the gene encoding mitofusin 2) interrupt mitochondrial fusion and cause the untreatable neurodegenerative condition Charcot-Marie-Tooth disease type 2A (CMT2A). It has not yet been possible to directl...
Alternative Titles
Full title
Correcting mitochondrial fusion by manipulating mitofusin conformations
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5315023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5315023
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature20156
