Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stres...
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Oxidative stress (OS), mitochondrial dysfunction, and dysregulation of alpha-synuclein (aSyn) homeostasis are key pathogenic factors in Parkinson’s disease. Nevertheless, the role of aSyn in mitochondrial physiology remains elusive. Thus, we addressed the impact of aSyn specifically on mitochondrial response to OS in neural cells. We characterize a...
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Full title
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5320486
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5320486
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep42942
