Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor t...
Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
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Author / Creator
Deng, X , Shao, G , Zhang, H-T , Li, C , Zhang, D , Cheng, L , Elzey, B D , Pili, R , Ratliff, T L , Huang, J and Hu, C-D
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Protein arginine methyltransferase 5 (PRMT5) is an emerging epigenetic enzyme that mainly represses transcription of target genes via symmetric dimethylation of arginine residues on histones H4R3, H3R8 and H2AR3. Accumulating evidence suggests that PRMT5 may function as an oncogene to drive cancer cell growth by epigenetic inactivation of several t...
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Full title
Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5322258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5322258
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/onc.2016.287
