Network topology of NaV1.7 mutations in sodium channel-related painful disorders
Network topology of NaV1.7 mutations in sodium channel-related painful disorders
About this item
Full title
Author / Creator
PROPANE Study Group , on behalf of the PROPANE Study Group , Kapetis, Dimos , Sassone, Jenny , Yang, Yang , Galbardi, Barbara , Xenakis, Markos N , Westra, Ronald L , Szklarczyk, Radek , Lindsey, Patrick , Faber, Catharina G , Gerrits, Monique , Merkies, Ingemar S J , Dib-Hajj, Sulayman D , Mantegazza, Massimo , Waxman, Stephen G and Lauria, Giuseppe
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Gain-of-function mutations in SCN9A gene that encodes the voltage-gated sodium channel NaV1.7 have been associated with a wide spectrum of painful syndromes in humans including inherited erythromelalgia, paroxysmal extreme pain disorder and small fibre neuropathy. These mutations change the biophysical properties of NaV1.7 channels leading to hyper...
Alternative Titles
Full title
Network topology of NaV1.7 mutations in sodium channel-related painful disorders
Authors, Artists and Contributors
Author / Creator
on behalf of the PROPANE Study Group
Kapetis, Dimos
Sassone, Jenny
Yang, Yang
Galbardi, Barbara
Xenakis, Markos N
Westra, Ronald L
Szklarczyk, Radek
Lindsey, Patrick
Faber, Catharina G
Gerrits, Monique
Merkies, Ingemar S J
Dib-Hajj, Sulayman D
Mantegazza, Massimo
Waxman, Stephen G
Lauria, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5324268
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5324268
Other Identifiers
ISSN
1752-0509
E-ISSN
1752-0509
DOI
10.1186/s12918-016-0382-0
