In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
About this item
Full title
Author / Creator
Suzuki, Keiichiro , Tsunekawa, Yuji , Hernandez-Benitez, Reyna , Wu, Jun , Zhu, Jie , Kim, Euiseok J. , Hatanaka, Fumiyuki , Yamamoto, Mako , Araoka, Toshikazu , Li, Zhe , Kurita, Masakazu , Hishida, Tomoaki , Li, Mo , Aizawa, Emi , Guo, Shicheng , Chen, Song , Goebl, April , Soligalla, Rupa Devi , Qu, Jing , Jiang, Tingshuai , Fu, Xin , Jafari, Maryam , Esteban, Concepcion Rodriguez , Berggren, W. Travis , Lajara, Jeronimo , Nuñez-Delicado, Estrella , Guillen, Pedro , Campistol, Josep M. , Matsuzaki, Fumio , Liu, Guang-Hui , Magistretti, Pierre , Zhang, Kun , Callaway, Edward M. , Zhang, Kang and Belmonte, Juan Carlos Izpisua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
A method for CRISPR-based genome editing that harnesses cellular non-homologous end joining activity to achieve targeted DNA knock-in in non-dividing tissues.
A novel method for knock-in gene integration
A current challenge in genome editing is achieving efficient targeted integration of transgenes in post-mitotic cells. These authors develop...
Alternative Titles
Full title
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
Authors, Artists and Contributors
Author / Creator
Tsunekawa, Yuji
Hernandez-Benitez, Reyna
Wu, Jun
Zhu, Jie
Kim, Euiseok J.
Hatanaka, Fumiyuki
Yamamoto, Mako
Araoka, Toshikazu
Li, Zhe
Kurita, Masakazu
Hishida, Tomoaki
Li, Mo
Aizawa, Emi
Guo, Shicheng
Chen, Song
Goebl, April
Soligalla, Rupa Devi
Qu, Jing
Jiang, Tingshuai
Fu, Xin
Jafari, Maryam
Esteban, Concepcion Rodriguez
Berggren, W. Travis
Lajara, Jeronimo
Nuñez-Delicado, Estrella
Guillen, Pedro
Campistol, Josep M.
Matsuzaki, Fumio
Liu, Guang-Hui
Magistretti, Pierre
Zhang, Kun
Callaway, Edward M.
Zhang, Kang
Belmonte, Juan Carlos Izpisua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5331785
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5331785
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature20565
