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Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334380

Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

About this item

Full title

Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

Publisher

Cham: Springer International Publishing

Journal title

Archivum Immunologiae et Therapiae Experimentalis, 2016-12, Vol.64 (Suppl 1), p.151-156

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Multiple myeloma (MM) is a plasma-cell malignancy derived from an early precursor of the B-cell lineage characterised by bone-marrow infiltration, lytic bone lesions, and the presence of a monoclonal protein in serum and/or urine. Interferon regulatory factor 4 (IRF4) is a critical transcriptional regulator in B-cell development and function that i...

Alternative Titles

Full title

Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334380

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5334380

Other Identifiers

ISSN

0004-069X

E-ISSN

1661-4917

DOI

10.1007/s00005-016-0442-6

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