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Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5336523

Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

About this item

Full title

Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2017-03, Vol.24 (3), p.309-315

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

smFRET analysis and colocalization spectroscopy reveal the mechanism of DNA entry into the Mcm2–7 helicase ring during replication origin licensing.
The opening and closing of two ring-shaped Mcm2–7 DNA helicases is necessary to license eukaryotic origins of replication, although the mechanisms controlling these events are unclear. The origin-re...

Alternative Titles

Full title

Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5336523

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5336523

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3375

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