Evidence for the principle of minimal frustration in the evolution of protein folding landscapes
Evidence for the principle of minimal frustration in the evolution of protein folding landscapes
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Theoretical and experimental studies have firmly established that protein folding can be described by a funneled energy landscape. This funneled energy landscape is the result of foldable protein sequences evolving following the principle of minimal frustration, which allows proteins to rapidly fold to their native biologically functional conformat...
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Full title
Evidence for the principle of minimal frustration in the evolution of protein folding landscapes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5338549
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5338549
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1613892114