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Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5343580

Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

About this item

Full title

Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-03, Vol.7 (1), p.44332-44332, Article 44332

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The synthetic cyclic hexapeptide cWFW (cyclo(RRRWFW)) has a rapid bactericidal activity against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has, however, remained elusive. In contrast to most antimicrobial peptides, cWFW neither permeabilizes the membrane nor translocates to the cytoplasm. Using a combination of prote...

Alternative Titles

Full title

Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5343580

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5343580

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep44332

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