Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Imiquimod (IMQ) produces a cutaneous phenotype in mice frequently studied as an acute model of human psoriasis. Whether this phenotype depends on strain or sex has never been systematically investigated on a large scale. Such effects, however, could lead to conflicts among studies, while further impacting study outcomes and efforts to translate res...
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Full title
Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345243
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345243
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-017-0415-3