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Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345243

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

About this item

Full title

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Publisher

England: BioMed Central

Journal title

Genome medicine, 2017-03, Vol.9 (1), p.24-24, Article 24

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Imiquimod (IMQ) produces a cutaneous phenotype in mice frequently studied as an acute model of human psoriasis. Whether this phenotype depends on strain or sex has never been systematically investigated on a large scale. Such effects, however, could lead to conflicts among studies, while further impacting study outcomes and efforts to translate res...

Alternative Titles

Full title

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345243

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345243

Other Identifiers

ISSN

1756-994X

E-ISSN

1756-994X

DOI

10.1186/s13073-017-0415-3

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