Cell cycle proteins as promising targets in cancer therapy
Cell cycle proteins as promising targets in cancer therapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Many cell cycle proteins are overexpressed or overactive in human cancers, in particular, D-type and E-type cyclins, cyclin-dependent kinases (CDK4, CDK6 and CDK2), Polo-like kinase 1 (PLK1) and Aurora kinases (Aurora A and Aurora B). In transgenic mice, overexpression of several of these cell cycle proteins induces or contributes to...
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Cell cycle proteins as promising targets in cancer therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5345933
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ISSN
1474-175X,1474-1768
E-ISSN
1474-1768
DOI
10.1038/nrc.2016.138
