Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides
Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Saturated aza-heterocycles are highly privileged building blocks that are commonly encountered in bioactive compounds and approved therapeutic agents. These N-heterocycles are also incorporated as chiral auxiliaries and ligands in asymmetric synthesis. As such, the development of methods to functionalize the α-methylene C–H bonds of these systems e...
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Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5347480
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5347480
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2619
