IRFinder: assessing the impact of intron retention on mammalian gene expression
IRFinder: assessing the impact of intron retention on mammalian gene expression
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called IRFinder to accurately detect IR from mRNA sequencing data. Analysis of 2573 samples showed that IR occurs in all tissues analyzed, affects over 80% of all coding genes and is associated with cell d...
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Full title
IRFinder: assessing the impact of intron retention on mammalian gene expression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5353968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5353968
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ISSN
1474-760X,1474-7596,1465-6906
E-ISSN
1474-760X
DOI
10.1186/s13059-017-1184-4
