Integrated genomic and molecular characterization of cervical cancer
Integrated genomic and molecular characterization of cervical cancer
About this item
Full title
Author / Creator
Eli &Edythe L. Broad Institute of Massachusetts Institute of Technology &Harvard University , Research Institute at Nationwide Children's Hospital , University of Alabama at Birmingham , McDonnell Genome Institute at Washington University , Washington University in St Louis , University of Wisconsin School of Medicine &Public Health , National Hospital, Abuja, Nigeria , Baylor College of Medicine , Barretos Cancer Hospital , Indiana University School of Medicine , Ontario Tumour Bank, The Ottawa Hospital , Massachusetts General Hospital , University of New Mexico Health Sciences Center , National Institute on Deafness &Other Communication Disorders , University of North Carolina at Chapel Hill , Buck Institute for Research on Aging , Cancer Genome Atlas Research Network , Medical College of Wisconsin , University of Abuja Teaching Hospital , University of Oklahoma Health Sciences Center , Institute of Human Virology , St Joseph's Candler Health System , University of Pittsburgh , University of Texas MD Anderson Cancer Center , National Cancer Institute , Montefiore Medical Center , University of Southern California , Institute for Systems Biology , University of Washington , Analytical Biological Services , Harvard Medical School , National Human Genome Research Institute , Memorial Sloan Kettering Cancer Center , Medical University of South Carolina , Ontario Tumour Bank, London Health Sciences Centre , SRA International , University of Kansas Medical Center , University of Lausanne , ILSbio, LLC , University of Bergen , University of California, Irvine , Canada's Michael Smith Genome Sciences Centre , International Genomics Consortium , Oregon Health &Science University , NantOmics , Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University , University of São Paulo, Ribeir ão Preto Medical School , HudsonAlpha Institute for Biotechnology , Albert Einstein College of Medicine , Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center , National Institute of Environmental Health Sciences , Van Andel Research Institute , Ontario Tumour Bank, Ontario Institute for Cancer Research , University of California Santa Cruz , Beckman Research Institute of City of Hope , Leidos Biomedical , Helen F. Graham Cancer Center &Research Institute at Christiana Care Health Services , The Cancer Genome Atlas Research Network , Saller, Charles , Tarvin, Katherine , Yau, Christina , Robertson, A. Gordon , Mungall, Karen , Lim, Lynette , Mar, Richard , Clarke, Amanda , Tam, Angela , Dhalla, Noreen , Carlsen, Rebecca , Holt, Robert A , Jones, Steven J. M , Hadjipanayis, Angela , Seidman, Jonathan , Rabeno, Brenda , Huelsenbeck-Dill, Lori , Iacocca, Mary , Petrelli, Nicholas , Adebamowo, Sally N , Adebamowo, Clement , Shelton, Candace , Crain, Daniel , Mallery, David , Curley, Erin , Gardner, Johanna , Shelton, Troy , Wu, Ye , Birrer, Michael , Miller, Christopher A , Fulton, Robert S , Appelbaum, Elizabeth L , Rader, Janet S , Behmaram, Behnaz , Bradley, William , Wrangle, John , Schultz, Nikolaus , Ladanyi, Marc , Felau, Ina , Zenklusen, Jean C , Demchok, John A , Sheth, Margi , Ferguson, Martin L , Tarnuzzer, Roy , Zhang, Jiashan , Wang, Zhining , Olaniyan, Olayinka , Sofia, Heidi J , Chen, Zhong , Saleh, Anthony D , Cheng, Hui , Parfitt, Jeremy , Albert, Monique , Sekhon, Harman , Gilbert, Sebastien , Myers, Jerome , Tucker, Kelinda , Lester, Jenny , Wan, Yunhu , Miller, Judy , Cherniack, Andrew D , Meyerson, Matthew , Voet, Doug , Kim, Jaegil , Lawrence, Michael S , Gehlenborg, Nils , Lin, Pei , Gabriel, Stacey B , Schumacher, Steven E , Leraas, Kristen M , Gastier-Foster, Julie M , Danilova, Ludmila , Salvesen, Helga B , Ju, Zhenlin , Diao, Lixia , Zhao, Hao , Ryan, Michael C , Averett Byers, Lauren , Yuan, Yuan , Bristow, Christopher A , Shaw, Kenna R. Mills , Radenbaugh, Amie , Chalise, Prabhakar , Godwin, Andrew K , Auman, J. Todd , Perou, Charles M , Veluvolu, Umadevi , Rathmell, W. Kimryn , Simons, Janae V , Mose, Lisle E , Shi, Yan , Thorne, Leigh B , Walker, Joan , Moore, Kathleen , McMeekin, Scott , Nelson, Tina , Bhargava, Rohit , Bootwalla, Moiz S , Triche, Timothy, Jr and Agnew, Kathy J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide. Here we report the extensive molecular characterization of 228 primary cervical cancers, one of the largest comprehensive genomic studies of cervical cancer to date. We observed notable APOBEC mutagenesis patterns and identified
SHKBP1
,
ERBB3
,
CAS...
Alternative Titles
Full title
Integrated genomic and molecular characterization of cervical cancer
Authors, Artists and Contributors
Author / Creator
Research Institute at Nationwide Children's Hospital
University of Alabama at Birmingham
McDonnell Genome Institute at Washington University
Washington University in St Louis
University of Wisconsin School of Medicine &Public Health
National Hospital, Abuja, Nigeria
Baylor College of Medicine
Barretos Cancer Hospital
Indiana University School of Medicine
Ontario Tumour Bank, The Ottawa Hospital
Massachusetts General Hospital
University of New Mexico Health Sciences Center
National Institute on Deafness &Other Communication Disorders
University of North Carolina at Chapel Hill
Buck Institute for Research on Aging
Cancer Genome Atlas Research Network
Medical College of Wisconsin
University of Abuja Teaching Hospital
University of Oklahoma Health Sciences Center
Institute of Human Virology
St Joseph's Candler Health System
University of Pittsburgh
University of Texas MD Anderson Cancer Center
National Cancer Institute
Montefiore Medical Center
University of Southern California
Institute for Systems Biology
University of Washington
Analytical Biological Services
Harvard Medical School
National Human Genome Research Institute
Memorial Sloan Kettering Cancer Center
Medical University of South Carolina
Ontario Tumour Bank, London Health Sciences Centre
SRA International
University of Kansas Medical Center
University of Lausanne
ILSbio, LLC
University of Bergen
University of California, Irvine
Canada's Michael Smith Genome Sciences Centre
International Genomics Consortium
Oregon Health &Science University
NantOmics
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
University of São Paulo, Ribeir ão Preto Medical School
HudsonAlpha Institute for Biotechnology
Albert Einstein College of Medicine
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
National Institute of Environmental Health Sciences
Van Andel Research Institute
Ontario Tumour Bank, Ontario Institute for Cancer Research
University of California Santa Cruz
Beckman Research Institute of City of Hope
Leidos Biomedical
Helen F. Graham Cancer Center &Research Institute at Christiana Care Health Services
The Cancer Genome Atlas Research Network
Saller, Charles
Tarvin, Katherine
Yau, Christina
Robertson, A. Gordon
Mungall, Karen
Lim, Lynette
Mar, Richard
Clarke, Amanda
Tam, Angela
Dhalla, Noreen
Carlsen, Rebecca
Holt, Robert A
Jones, Steven J. M
Hadjipanayis, Angela
Seidman, Jonathan
Rabeno, Brenda
Huelsenbeck-Dill, Lori
Iacocca, Mary
Petrelli, Nicholas
Adebamowo, Sally N
Adebamowo, Clement
Shelton, Candace
Crain, Daniel
Mallery, David
Curley, Erin
Gardner, Johanna
Shelton, Troy
Wu, Ye
Birrer, Michael
Miller, Christopher A
Fulton, Robert S
Appelbaum, Elizabeth L
Rader, Janet S
Behmaram, Behnaz
Bradley, William
Wrangle, John
Schultz, Nikolaus
Ladanyi, Marc
Felau, Ina
Zenklusen, Jean C
Demchok, John A
Sheth, Margi
Ferguson, Martin L
Tarnuzzer, Roy
Zhang, Jiashan
Wang, Zhining
Olaniyan, Olayinka
Sofia, Heidi J
Chen, Zhong
Saleh, Anthony D
Cheng, Hui
Parfitt, Jeremy
Albert, Monique
Sekhon, Harman
Gilbert, Sebastien
Myers, Jerome
Tucker, Kelinda
Lester, Jenny
Wan, Yunhu
Miller, Judy
Cherniack, Andrew D
Meyerson, Matthew
Voet, Doug
Kim, Jaegil
Lawrence, Michael S
Gehlenborg, Nils
Lin, Pei
Gabriel, Stacey B
Schumacher, Steven E
Leraas, Kristen M
Gastier-Foster, Julie M
Danilova, Ludmila
Salvesen, Helga B
Ju, Zhenlin
Diao, Lixia
Zhao, Hao
Ryan, Michael C
Averett Byers, Lauren
Yuan, Yuan
Bristow, Christopher A
Shaw, Kenna R. Mills
Radenbaugh, Amie
Chalise, Prabhakar
Godwin, Andrew K
Auman, J. Todd
Perou, Charles M
Veluvolu, Umadevi
Rathmell, W. Kimryn
Simons, Janae V
Mose, Lisle E
Shi, Yan
Thorne, Leigh B
Walker, Joan
Moore, Kathleen
McMeekin, Scott
Nelson, Tina
Bhargava, Rohit
Bootwalla, Moiz S
Triche, Timothy, Jr
Agnew, Kathy J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5354998
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5354998
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature21386
