Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillat...
Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Contents
Parkinson's disease is a movement disorder caused by dopamine depletion in the basal ganglia. Abnormally synchronized neuronal oscillations between 8 and 15 Hz in the basal ganglia are implicated in motor symptoms of Parkinson's disease. However, how these abnormal oscillations are generated and maintained in the dopamine-depleted state is unknown....
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Full title
Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5359256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5359256
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ISSN
1662-5129
E-ISSN
1662-5129
DOI
10.3389/fnana.2017.00021
