Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model
Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model
About this item
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Author / Creator
Simão, D , Pinto, C , Fernandes, P , Peddie, C J , Piersanti, S , Collinson, L M , Salinas, S , Saggio, I , Schiavo, G , Kremer, E J , Brito, C and Alves, P M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Gene therapy is a promising approach with enormous potential for treatment of neurodegenerative disorders. Viral vectors derived from canine adenovirus type 2 (CAV-2) present attractive features for gene delivery strategies in the human brain, by preferentially transducing neurons, are capable of efficient axonal transport to afferent brain structu...
Alternative Titles
Full title
Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5367519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5367519
Other Identifiers
ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/gt.2015.75
