Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo
Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo
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Author / Creator
Alsadeq, A , Strube, S , Krause, S , Carlet, M , Jeremias, I , Vokuhl, C , Loges, S , Aguirre-Ghiso, J A , Trauzold, A , Cario, G , Stanulla, M , Schrappe, M and Schewe, D M
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
P38α/β has been described as a tumor-suppressor controlling cell cycle checkpoints and senescence in epithelial malignancies. However, p38α/β also regulates other cellular processes. Here, we describe a role of p38α/β as a regulator of acute lymphoblastic leukemia (ALL) proliferation and survival in experimental ALL models. We also report first evi...
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Full title
Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5370559
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5370559
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.153