Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis
Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis
About this item
Full title
Author / Creator
Gilles, Laure , Arslan, Ahmet Dirim , Marinaccio, Christian , Wen, Qiang Jeremy , Arya, Priyanka , McNulty, Maureen , Yang, Qiong , Zhao, Jonathan C , Konstantinoff, Katerina , Lasho, Terra , Pardanani, Animesh , Stein, Brady , Plo, Isabelle , Sundaravel, Sriram , Wickrema, Amittha , Migliaccio, Annarita , Gurbuxani, Sandeep , Vainchenker, William , Platanias, Leonidas C , Tefferi, Ayalew and Crispino, John D
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Primary myelofibrosis (PMF) is a clonal hematologic malignancy characterized by BM fibrosis, extramedullary hematopoiesis, circulating CD34+ cells, splenomegaly, and a propensity to evolve to acute myeloid leukemia. Moreover, the spleen and BM of patients harbor atypical, clustered megakaryocytes, which contribute to the disease by secreting profib...
Alternative Titles
Full title
Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis
Authors, Artists and Contributors
Author / Creator
Arslan, Ahmet Dirim
Marinaccio, Christian
Wen, Qiang Jeremy
Arya, Priyanka
McNulty, Maureen
Yang, Qiong
Zhao, Jonathan C
Konstantinoff, Katerina
Lasho, Terra
Pardanani, Animesh
Stein, Brady
Plo, Isabelle
Sundaravel, Sriram
Wickrema, Amittha
Migliaccio, Annarita
Gurbuxani, Sandeep
Vainchenker, William
Platanias, Leonidas C
Tefferi, Ayalew
Crispino, John D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5373858
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5373858
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI82905
